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Beyond its central mitochondrial-mediated effects, Ashwagandhas anticancer activity is further enhanced through multiple mechanisms, including inhibition of angiogenesis, suppression of metastasis, induction of cell cycle arrest, disruption of mitosis via Withanones interaction with the TPX2-Aurora A complex, and impairment of cellular energy metabolism through inhibition of succinate dehydrogenase [94, 98, 219, 220]